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[The frequency of polymorphism in promoter gene coding epoxygenase 2J2 in patents with acute coronary syndrome].

TSitologiia i genetika (2010-05-20)
A O Lisovoĭ, V E Dosenko, A N Parkhomenko, A A Moĭbenko
RESUMEN

G(-50) --> T promoter polymorphism of gene encoding human epoxygenase 2J2 in 107 patients with acute coronary syndrome and in 104 practically healthy people was determined. It was shown that interrelation of genotypes G/G, G/T and T/T was 91%, 9% Ta 0% correspondingly (in control--92%, 7%, 1%; P > 0.05 by chi2-test). The data indicate that epoxygenase 2J2 gene polymorphism is not a risk factor of acute coronary syndrome in Ukrainian population.