Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Chemical communications (Cambridge, England) (2013-02-26)

Lorraine Blackmore, Roisin Moriarty, Ciaran Dolan, Kellie Adamson, Robert J Forster, Marc Devocelle, Tia E Keyes

RESUMEN

The targeted delivery of luminescent Ru(II) polypyridyl complexes to the nucleus of live mammalian cells by a Nuclear Localisation Signal (NLS) peptide; NF-κB is demonstrated.

MATERIALES

Referencia del producto

Marca

Descripción del producto

545023

Sigma-Aldrich

Ruthenium, powder

326712

Sigma-Aldrich

Ruthenium black

209694

Sigma-Aldrich

Ruthenium, powder, −200 mesh, 99.9% trace metals basis