Saltar al contenido
Merck

New multicomponent approach for the synthesis of benzo[c]coumarin derivatives over MgO under solvent-free conditions.

Molecular diversity (2010-07-24)
Hassan Valizadeh, Ashraf Fakhari
RESUMEN

In this study, a three-component one-pot synthesis of select 5-amino-6-cyano-3-hydroxybenzo[c]coumarin compounds derived from salicylaldehydes, malononitrile, and ethyl acetoacetate is reported. The reaction is conducted on grinding over MgO at room temperature resulting in good yields.

MATERIALES
Referencia del producto
Marca
Descripción del producto

Sigma-Aldrich
Ethyl acetoacetate, ReagentPlus®, 99%
Sigma-Aldrich
Ethyl acetoacetate, natural, ≥97%, FG
Sigma-Aldrich
Ethyl acetoacetate, ≥99%, FCC, FG
Sigma-Aldrich
Ethyl acetoacetate, puriss. p.a., ≥99.0% (GC)
Sigma-Aldrich
Ethyl acetoacetate, Arxada quality, ≥99.0% (GC)