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Merck

Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole.

Chemical communications (Cambridge, England) (2008-03-28)
Jun-Long Zhang, Dewain K Garner, Lei Liang, Qian Chen, Yi Lu
RESUMEN

We demonstrate that incorporation of MnSalen into a protein scaffold enhances the chemoselectivity in sulfoxidation of thioanisole and find that both the polarity and hydrogen bonding of the protein scaffold play an important role in tuning the chemoselectivity.

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Sigma-Aldrich
Thioanisole, ReagentPlus®, ≥99%