An Au-catalyzed cyclialkylation of electron-rich arenes with epoxides to prepare 3-chromanols.

An Au-catalyzed cyclialkylation of electron-rich arenes with epoxides to prepare 3-chromanols.

Journal of the American Chemical Society (2004-05-13)

Zhangjie Shi, Chuan He

RESUMEN

A gold-catalyzed cyclialkylation of electron-rich arenes with tethered epoxides afforded 3-chromanols stereospecifically.

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Sigma-Aldrich

1,2,3-Trimethoxybenzene, 98%