Saltar al contenido
Merck

Mammalian ceramide synthases.

IUBMB life (2010-03-12)
Michal Levy, Anthony H Futerman
RESUMEN

In mammals, ceramide, a key intermediate in sphingolipid metabolism and an important signaling molecule, is synthesized by a family of six ceramide synthases (CerS), each of which synthesizes ceramides with distinct acyl chain lengths. There are a number of common biochemical features between the CerS, such as their catalytic mechanism, and their structure and intracellular localization. Different CerS also display remarkable differences in their biological properties, with each of them playing distinct roles in processes as diverse as cancer and tumor suppression, in the response to chemotherapeutic drugs, in apoptosis, and in neurodegenerative diseases.

MATERIALES
Referencia del producto
Marca
Descripción del producto

Avanti
C8 PEG750 Ceramide, Avanti Research - A Croda Brand 880670P, powder
Avanti
C16 PEG750 Ceramide, Avanti Research - A Croda Brand 880680P, powder