Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.

Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.

Bioorganic & medicinal chemistry letters (2006-04-20)

William J Watkins, James M Chen, Aesop Cho, Lee Chong, Nicole Collins, Maria Fardis, Wei Huang, Magdeleine Hung, Thorsten Kirschberg, William A Lee, Xiaohong Liu, William Thomas, Jie Xu, Ameneh Zeynalzadegan, Jennifer Zhang

PMID16621550

RESUMEN

The design, synthesis, and IMPDH inhibitory activity of a series of phosphonic acid-containing analogues of mycophenolic acid are described.

MATERIALES

Referencia del producto

Marca

Descripción del producto

M5255

Sigma-Aldrich

Mycophenolic acid, ≥98%

M3536

Sigma-Aldrich

Mycophenolic acid, powder, BioReagent, suitable for cell culture