SAB4300263

Anti-phospho-CFL1/CFL2 (pTyr⁸⁸) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-CFL antibody produced in rabbit, Anti-NEM7 antibody produced in rabbit, Anti-cofilin 1 (non-muscle) / cofilin 2 (muscle) antibody produced in rabbit
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: ~19 kDa
• reactividad de especies: human, mouse, rat
• concentración: 1 mg/mL
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• isotipo: IgG
• secuencia del inmunógeno: (A-T-YP-E-T)
• Nº de acceso NCBI: NP_005498.1; NP_068733.1
• Nº de acceso UniProt: P23528
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr88)
• Información sobre el gen: human ... CFL1(1072) , CFL2(1073)

Descripción

Inmunógeno

Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T), according to the protein CFL1/CFL2.

Características y beneficios

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Descripción de destino

Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable