SAB3500033

Anti-ZBED3 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution, ab2

• Sinónimos: Anti-Zinc finger BED-type domain containing 3
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: predicted mol wt 26 kDa
• reactividad de especies: human, rat, mouse
• técnicas: indirect ELISA: suitable; western blot: suitable
• Nº de acceso NCBI: NP_115743
• Nº de acceso UniProt: Q96IU2
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... ZBED3(84327)

Descripción

Inmunógeno

ZBED3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human ZBED3.

Características y beneficios

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Descripción de destino

Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.

Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP3500033.

Forma física

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable