NE1015
Anti-Glial Fibrillary Acidic Protein Cocktail Mouse mAb (SMI-22)
liquid, clone SMI-22, Calbiochem®
Sinónimos:
Anti-GFAP Cocktail
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100 μL
497,00 €
497,00 €
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100 μL
497,00 €
About This Item
Código UNSPSC:
12352203
NACRES:
NA.43
497,00 €
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origen biológico
mouse
Nivel de calidad
forma del anticuerpo
ascites fluid
tipo de anticuerpo
primary antibodies
clon
SMI-22, monoclonal
Formulario
liquid
contiene
≤0.1% sodium azide as preservative
reactividad de especies
human, bovine, mouse, guinea pig, porcine, sheep, canine, rat, chicken
fabricante / nombre comercial
Calbiochem®
condiciones de almacenamiento
OK to freeze
avoid repeated freeze/thaw cycles
isotipo
IgG2b
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... GFAP(2670)
Descripción general
Mouse monoclonal antibody cocktail that contains a mixture of 3 antibodies supplied as undiluted ascites. Recognizes the ~50 kDa glial fibrillary acidic protein.
Recognizes ~50 kDa glial fibrillary acidic protein (GFAP) in human and bovine cytoskeletal preparations.
This Anti-Glial Fibrillary Acidic Protein Cocktail Mouse mAb is validated for use in ELISA, Frozen Sections, WB, ICC, Paraffin Sections for the detection of Glial Fibrillary Acidic Protein.
Inmunógeno
Bovine
purified bovine GFAP protein
Aplicación
ELISA (1:1000)
Frozen Sections (1:1000, see comments)
Immunoblotting (1:1000)
Immunocytochemistry (1:1000, see comments)
Paraffin Sections (1:1000, trypsin or heat pre-treatment required)
Advertencia
Toxicity: Standard Handling (A)
Forma física
Undiluted ascites.
Reconstitución
Upon initial thaw, aliquot and freeze (-20°C).
Nota de análisis
Positive Control
Astrocytes or cytoskeletal preparations
Astrocytes or cytoskeletal preparations
Otras notas
This cocktail is derived from the Bigner-Eng clones MAb1B4, MAb2E1, and MAb4A11 and provides a means for more comprehensive detection of astrocytomas than each clone alone. Each component is specific for GFAP and stains astrocytes and astrocytic processes as well as Bergman glia. Recognizes both anaplastic and reactive astrocytes by immunocytochemical staining. Does not recognize metastatic tumors and brain tumors of non-astrocytic origin, including medulloblastomas, meningiomas, choroid plexus papillomas, and schwannomas. For staining paraffin sections it is recommended that de-paraffinized sections be treated with 0.1% trypsin in 50 mM Tris-HCl, pH 7.6 for 20-30 min at 37°C or boiled in Tris-buffered saline, pH 9.0 for 15 min to expose the epitope. For immunocytochemistry or staining frozen sections, post-fixation in cold methanol or methanol/hydrogen peroxide for 10 min is required for access to the astrocytes in the sample. Antibody should be titrated for optimal results in individual systems.
Vick, W.W., et al. 1987. Acta. Cytol.31, 816.
McLendon R.E., et al. 1986. J. Neuropathol. Exp. Neurol.45, 692.
Pegram, C.N., et al. 1985. Neurochem. Pathol.3, 119.
McLendon R.E., et al. 1986. J. Neuropathol. Exp. Neurol.45, 692.
Pegram, C.N., et al. 1985. Neurochem. Pathol.3, 119.
Información legal
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Certificados de análisis (COA)
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