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MAB5442

Sigma-Aldrich

Anti-Collapsin Response Mediated Protein 5 Antibody, clone CR-1

culture supernatant, clone CR-1, Chemicon®

Sinónimos:

CRMP5, DRP-5, ULIP-6, CRAM

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rat

Nivel de calidad

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

CR-1, monoclonal

reactividad de especies

rat, human, bovine

fabricante / nombre comercial

Chemicon®

técnicas

immunohistochemistry: suitable
western blot: suitable

isotipo

IgG1

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... DPYSL5(56896)

Especificidad

Collapsin response mediated protein-5 (CRMP-5). The antibody binds to a region of the human protein from between ~369 to 564 amino acids.

Inmunógeno

CRMP-5 purified from rat and human brain.

Aplicación

Anti-Collapsin Response Mediated Protein 5 Antibody, clone CR-1 detects level of Collapsin Response Mediated Protein 5 & has been published & validated for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance
Western blot: 1:500-1:2,000 on human and rat brain extracts. 1:500-1:2,000 on human small-cell lung carcinoma. 1:1,500-1:6,000 on bovine retina and optic nerve extracts.

Immunohistochemistry: 1:50-1:200 on bovine retina frozen sections fixed with 10% formalin. No reactivity on mouse cerebellum.

Protein isolation: Bound to Bio-Rad′s Affi-gel (cat# 153-6046) to pull out native CRMP-5 from aqueous extracts of brain.

Optimal working dilutions must be determined by end user.

Forma física

Unpurified tissue culture supernatant from a perfusion system, filtered through a 0.2μ micron membrane prior to vialing. Product contains 20%FBS and Ciprofloxacin at final concentration of 10μg/mL.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Uses of the CR-1 and CR-3 antibodies are covered under pending patent application(s) assigned to the Mayo Foundation for Medical Education and Research (MFMER) and are proprietary to MFMER. Academic not-for-profit research institutions are granted an automatic license with the purchase of this product to use the antibody only for internal, non-sponsored, non-commercial, academic research purposes which license specifically excludes the right to sell, or otherwise transfer the antibody or its derivatives to third parties. In accepting this license, all users acknowledge that the CR-1 and CR-3 antibodies are experimental in nature. MFMER makes no warranties, express or implied of any kind, and hereby disclaims any warranties, representations, or guarantees of any kind as to the CR-1 and CR-3 antibodies, patents or product. All others are invited to request a license from MFMER prior to purchasing this antibody or using it for any purpose. For license information, please contact Mayo Medical Ventures, Office of Technology Commercialization at (507) 284-8878.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Gladiola Goranci-Buzhala et al.
Cell reports, 31(10), 107738-107738 (2020-06-11)
Glioblastoma (GBM) possesses glioma stem cells (GSCs) that exhibit aggressive invasion behavior in the brain. Current preclinical GBM invasion assays using mouse brain xenografts are time consuming and less efficient. Here, we demonstrate an array of methods that allow rapid

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