8.20122

Benzamidine hydrochloride hydrate

for synthesis

• Sinónimos: Benzamidine hydrochloride hydrate
• Fórmula empírica (notación de Hill): C₇H₈N₂ · xHCl · yH₂O
• Número de CAS: 206752-36-5
• Peso molecular: 120.15 (anhydrous free base basis)
• Número MDL: MFCD00066285
• Código UNSPSC: 12352107
• Número índice de la CE: 216-795-4
• NACRES: NA.22

Propiedades

• Nivel de calidad: 200
• Análisis: ≥98.5% (HPLC)
• formulario: powder
• pH: 5 (20 °C, 50 g/L in H₂O)
• mp: 80-84 °C
• temp. de almacenamiento: 2-30°C
• InChI: 1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)/p+1
• Clave InChI: PXXJHWLDUBFPOL-UHFFFAOYSA-O

Descripción

Aplicación

• Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes.: This study investigates the interaction of benzamidine hydrochloride hydrate as a serine protease inhibitor, focusing on its binding mechanism in the presence of water molecules. Utilizing neutron crystallography, the research provides insights into the dynamic role of water in enhancing the binding affinity and stability of the inhibitor to trypsin. This understanding is crucial for the design of more effective protease inhibitors in pharmaceutical applications (Schiebel et al., 2018).

Nota de análisis

Assay (HPLC, area%): ≥ 98.5 % (a/a)
Water (K. F.): 7.0 - 13.0 %
Identity (IR): passes test

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable