581004

Telomerase Inhibitor III, Sodium Salt

The Telomerase Inhibitor III, Sodium Salt controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.

• Sinónimos: TAG-6, 5ʹ-d(TTAGGG)-3ʹ
• Código UNSPSC: 12352200

Propiedades

• Nivel de calidad: 100
• formulario: lyophilized
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated (hygroscopic); protect from light
• solubilidad: water: soluble
• Condiciones de envío: wet ice
• temp. de almacenamiento: −70°C

Descripción

Descripción general

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomer mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM.

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomere mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM. Note: 150 nmol = 285 µg.

M.W. ~1900.

Acciones bioquímicas o fisiológicas

Cell permeable: yes

Primary Target
Telomerase activity in cell lysates

Product competes with ATP.

Reversible: no

Envase

Packaged under inert gas

Advertencia

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Secuencia

5′-d(TTAGGG)-3′

Otras notas

Mata, J.E., et al. 1997. Toxicol. Appl. Pharmacol. 144, 189.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable