116833

Adenosine 3′,5′-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2′-O-Methyl-, Sodium Salt

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC).

• Sinónimos: Adenosine 3′,5′-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2′-O-Methyl-, Sodium Salt, 8-CPT-2ʹ-O-Me-cAMP, Na
• Fórmula empírica (notación de Hill): C₁₇H₁₆ClN₅O₆PS · Na
• Peso molecular: 507.82
• Código UNSPSC: 12352208

Propiedades

• Nivel de calidad: 100
• Análisis: ≥98% (HPLC)
• formulario: lyophilized
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated (hygroscopic)
• solubilidad: water: 10 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) (also called cAMP-guanine nucleotide-exchange factors or cAMP-GEF) in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA. 5 µmol = 2.54 mg. λmax = 282 nm.

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) [also called cAMP-guanine nucleotide-exchange factors (cAMP-GEF)] in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA.

Note: 5 µmol = 2.54 mg.

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Otras notas

Kang, G., et al. 2003. J. Biol. Chem.278, 8279.
Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.

Información legal

Sold under license of European Patent Application 02/077,219.0.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable