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Merck

WT1

Wilms tumor 1

Sinónimos:
AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
Especie:
Human WT1 (7490), Mouse Wt1 (22431), Rat Wt1 (24883), domestic guinea pig Wt1 (100716139), dog WT1 (609253), sheep WT1 (100101227), naked mole-rat Wt1 (101714640), cow WT1 (280959), chicken WT1 (396139), cow WT1 (782183) ...Más
ID UniProtKB:
P19544, A8K6S1, B3KSA5, Q15881, Q16256, Q16575, Q4VXV4, Q4VXV5
ID del gen:
  • Human(7490) Summary: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
  • Mouse(22431) Wilms tumor 1 homolog
  • Rat(24883) Wilms tumor 1
  • domestic guinea pig(100716139) Wilms tumor 1
  • dog(609253) Wilms tumor 1
  • sheep(100101227) Wilms tumor 1
  • naked mole-rat(101714640) Wilms tumor 1
  • cow(280959) Wilms tumor 1
  • chicken(396139) Wilms tumor 1
  • cow(782183) Wilms tumor 1
  • cow(614584) Wilms tumor 1
  • domestic cat(101088518) Wilms tumor 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
348M-9
WT1 (6F-H2) Mouse Monoclonal Antibody, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
MAB4234
Anti-Wilms′ Tumor Antibody, NT, clone 6F-H2, clone 6F-H2, Chemicon®, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
05-753
Anti-WT1 Antibody, clone 6F-H2, clone 6F-H2, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunohistochemistry
western blot
MAB4234-C
Anti-Wilms′ Tumor Antibody, NT clone 6F-H2, Ascites Free, clone 6F-H2, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB2108752
Anti-WT1, affinity isolated antibody,
Reactividad de especies
dog, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
SRP2082
WT-1 (+KTS) human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
Especie
human
SRP2083
WT-1 (-KTS) human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU083661
MISSION® esiRNA, targeting human WT1,
Especie
human