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Merck

TNFRSF18

tumor necrosis factor receptor superfamily, member 18

Sinónimos:
AITR, CD357, GITR, GITR-D
Especie:
ID UniProtKB:
ID del gen:
  • Human(8784) Summary: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
  • Mouse(21936) tumor necrosis factor receptor superfamily, member 18
  • Rat(500598) tumor necrosis factor receptor superfamily, member 18
  • sheep(101108672) tumor necrosis factor receptor superfamily, member 18
  • domestic cat(101083251) tumor necrosis factor receptor superfamily, member 18
  • domestic guinea pig(100715459) tumor necrosis factor receptor superfamily, member 18
  • naked mole-rat(101715065) tumor necrosis factor receptor superfamily, member 18
  • cow(516256) tumor necrosis factor receptor superfamily, member 18
  • dog(606971) tumor necrosis factor receptor superfamily, member 18
  • Zebrafish(571217) tumor necrosis factor receptor superfamily, member 18
  • chicken(419424) tumor necrosis factor receptor superfamily, member 18

Custom & Knockdown Gene Products

ELISA

Número de producto
Descripción
Especie
Human GITR / TNFRSF18 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Especie
human
Mouse Tnfrsf18 ELISA Kit, ,
Especie
mouse
Human GITR / TNFRSF18 ELISA Kit, for cell and tissue lysates,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-TNFRSF18 (soluble form) Antibody, clone T10P2H9*B9, clone T10P2H9*B9, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-hGITR Antibody, clone 108-17, clone 108-17, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Proteins

Número de producto
Descripción
Especie
CD40, FC Fusion, recombinant, expressed in HEK 293 cells,
Especie
human
GITR (CD357), FC Fusion, recombinant, expressed in HEK 293 cells,
Especie
human
GITR (CD357), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Especie
human