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Merck

TEF

thyrotrophic embryonic factor

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(7008) Summary: This gene encodes a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(21685) thyrotroph embryonic factor
  • Rat(29362) thyrotrophic embryonic factor
  • fruit fly(36920) teflon
  • chicken(396342) thyrotrophic embryonic factor
  • dog(607883) thyrotrophic embryonic factor
  • domestic cat(101100493) thyrotrophic embryonic factor
  • cow(616076) thyrotrophic embryonic factor
  • sheep(100192430) thyrotrophic embryonic factor
  • Domestic Rabbit(100353476) thyrotrophic embryonic factor
  • domestic guinea pig(100715603) thyrotrophic embryonic factor
  • naked mole-rat(101708629) thyrotrophic embryonic factor

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TEF, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-TEF antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, human, mouse, sheep
Aplicación
western blot
Anti-TEF antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
horse, human
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TEF,
Especie
human
MISSION® esiRNA, targeting mouse Tef,
Especie
mouse