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Merck

TAPBP

TAP binding protein (tapasin)

Sinónimos:
NGS17, TAPA, TPN, TPSN
Especie:
ID UniProtKB:
ID del gen:
  • Human(6892) Summary: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(21356) TAP binding protein
  • Rat(25217) TAP binding protein (tapasin)
  • dog(481740) TAP binding protein (tapasin)
  • naked mole-rat(101719224) TAP binding protein (tapasin)
  • chicken(417048) TAP binding protein (tapasin)
  • Zebrafish(30163) TAP binding protein
  • domestic cat(101091023) TAP binding protein (tapasin)
  • sheep(100170652) TAP binding protein (tapasin)
  • domestic guinea pig(100735947) TAP binding protein (tapasin)
  • Horse(100061515) TAP binding protein (tapasin)
  • cow(504335) TAP binding protein (tapasin)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Tapasin Antibody, clone 7F6, clone 7F6, from rat,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-TAPBP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Tapasin, from rabbit,
Reactividad de especies
mouse
Aplicación
immunoprecipitation (IP)
western blot
Anti-TAPBP antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-TAPBP antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, horse, human, mouse, pig, rat, sheep
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TAPBP (2),
Especie
human
MISSION® esiRNA, targeting human TAPBP (1),
Especie
human