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Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Sinónimos:
ASV, SRC1, c-SRC, p60-Src
Especie:
Human SRC (6714), Mouse Src (20779), Rat Src (83805), Zebrafish src (325084), chicken SRC (396442), domestic cat SRC (101100378), dog SRC (485864), sheep SRC (101103084), cow SRC (535742), domestic guinea pig Src (100728509)
ID UniProtKB:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
ID del gen:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
695017
Ácido fosfórico, ACS reagent, ≥85 wt. % in H2O,
Especie
human
345245
Ácido fosfórico, 85 wt. % in H2O, 99.99% trace metals basis,
Especie
human
438081
Ácido fosfórico, ACS reagent, ≥85 wt. % in H2O,
Especie
human
27109
Ácido cítrico, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance),
Especie
human
466123
Ácido fosfórico, crystalline, ≥99.999% trace metals basis,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
05-677
Anticuerpo anti-fosfo-Src (Tyr416), clon 9A6, clone 9A6, Upstate®, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunoprecipitation (IP)
western blot
07-909
Anti-phospho-Src (Tyr418) Antibody, Upstate®, from rabbit,
Reactividad de especies
chicken, human, mouse
Aplicación
immunocytochemistry
immunohistochemistry
western blot
HPA030875
Anti-SRC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
04-772
Anti-Src Antibody, CT, clone NL19 | 04-772, clone NL19, Upstate®, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot
SAB5300367
Monoclonal Anti-SRC antibody produced in mouse, clone 1F11, ascites fluid,
Reactividad de especies
human
Aplicación
ELISA
flow cytometry
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
S9692
SU 6656, ≥98% (HPLC),
Especie
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Especie
human, rat
E2250
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Especie
human, rat
T182
Tyrphostin A9, solid,
Especie
mouse, human
SML2589
Dasatinib, ≥98% (HPLC),
Especie
human

Kits

Referencia del producto
Descripción
Especie
20-121
Src Kinase Reaction Buffer, ,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Especie
human
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Especie
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Especie
human
14-746-M
Src (1-530) Protein, active, 10 µg, ,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU071351
MISSION® esiRNA, targeting mouse Src,
Especie
mouse

Small Molecule - Substrate

Referencia del producto
Descripción
Especie
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Especie
human