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Merck

SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

Sinónimos:
OAT4L, RST, URAT1
Especie:
Human SLC22A12 (116085), Mouse Slc22a12 (20521), Rat Slc22a12 (365398), cow SLC22A12 (526067), Horse SLC22A12 (100055832), naked mole-rat Slc22a12 (101714998), domestic guinea pig Slc22a12 (100721051), domestic cat SLC22A12 (101100592), dog SLC22A12 (483761), sheep SLC22A12 (101117630)
ID UniProtKB:
Q96S37, B7WPG1, Q19PF7, Q19PF8, Q19PF9, Q19PG0, Q6UXW3, Q96DT2
ID del gen:
  • Human(116085) Summary: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
  • Mouse(20521) solute carrier family 22 (organic anion/cation transporter), member 12
  • Rat(365398) solute carrier family 22 (organic anion/urate transporter), member 12
  • cow(526067) solute carrier family 22 (organic anion/urate transporter), member 12
  • Horse(100055832) solute carrier family 22 (organic anion/urate transporter), member 12
  • naked mole-rat(101714998) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic guinea pig(100721051) solute carrier family 22 (organic anion/urate transporter), member 12
  • domestic cat(101100592) solute carrier family 22 (organic anion/urate transporter), member 12
  • dog(483761) solute carrier family 22 (organic anion/urate transporter), member 12
  • sheep(101117630) solute carrier family 22 (organic anion/urate transporter), member 12

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA024575
Anti-SLC22A12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
SAB1403444
Monoclonal Anti-SLC22A12 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
SAB1410203
Anti-SLC22A12 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
SML1607
Lesinurad, ≥98% (HPLC),
Especie
human
S9509
(±)-Sulfinpyrazone, analytical standard,
Especie
human
Y0000775
Benzbromarone, European Pharmacopoeia (EP) Reference Standard,
Especie
human
09147
Benzbromarone, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Especie
human
S2159000
Sulfinpyrazone, European Pharmacopoeia (EP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU158401
MISSION® esiRNA, targeting human SLC22A12,
Especie
human