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Merck

SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Sinónimos:
EAAT2, GLT-1
Especie:
ID UniProtKB:
ID del gen:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Especie
rat
Dihydrokainic acid, ≥98% (HPLC), powder,
Especie
rat, human
(±)-AMPA, solid,
Especie
rat
Ácido kaínico monohydrate, ≥99% (TLC),
Especie
human, mouse, rat
(Aminomethyl)phosphonic acid, 99%,
Especie
rat, human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-transportador del glutamato, glial, serum, Chemicon®,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Excitatory amino acid transporter 2 Antibody, clone G6, clone G6, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Dihydrokainic acid, ≥98% (HPLC), powder,
Especie
rat, human
(Aminomethyl)phosphonic acid, 99%,
Especie
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Especie
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Especie
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Especie
rat, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SLC1A2,
Especie
human