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Merck

SFTPB

surfactant protein B

Sinónimos:
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
Especie:
Human SFTPB (6439), Mouse Sftpb (20388), Rat Sftpb (192155), naked mole-rat Sftpb (101700017), domestic guinea pig Sftpb (100379548), dog SFTPB (100688334), Horse SFTPB (100034028), domestic cat SFTPB (101091359), sheep SFTPB (443043), cow SFTPB (507398)
ID UniProtKB:
P07988, Q96R04
ID del gen:
  • Human(6439) Summary: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
  • Mouse(20388) surfactant associated protein B
  • Rat(192155) surfactant protein B
  • naked mole-rat(101700017) surfactant protein B
  • domestic guinea pig(100379548) surfactant associated protein B
  • dog(100688334) surfactant protein B
  • Horse(100034028) surfactant protein B
  • domestic cat(101091359) surfactant protein B
  • sheep(443043) surfactant protein B
  • cow(507398) surfactant protein B

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
SAB5600258
Anti-SP-B (Surfactant protein B) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM370, purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
SAB2102128
Anti-SFTPB antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
dog, guinea pig, human, rat
Aplicación
immunohistochemistry
western blot
ABS21
Anticuerpo anti-proteína surfactante B, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
HPA062148
Anti-SFTPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
AB3430
Anti-Prosurfactant Protein B Antibody, reacts with both CT and NT, serum, Chemicon®,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunohistochemistry
western blot

esiRNA

Número de producto
Descripción
Especie
EHU123801
MISSION® esiRNA, targeting human SFTPB,
Especie
human