PTGIS
prostaglandin I2 (prostacyclin) synthase
Sinónimos:
CYP8, CYP8A1, PGIS, PTGI
Especie:
Human PTGIS (5740), Mouse Ptgis (19223), Rat Ptgis (25527), dog PTGIS (485919), Goat PTGIS (100860894), cow PTGIS (282021), domestic guinea pig Ptgis (100734621), Zebrafish ptgis (559148), sheep PTGIS (101116418), Horse PTGIS (100071412) ...Más
ID UniProtKB:
ID del gen:
- Human(5740) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
- Mouse(19223) prostaglandin I2 (prostacyclin) synthase
- Rat(25527) prostaglandin I2 (prostacyclin) synthase
- dog(485919) prostaglandin I2 (prostacyclin) synthase
- Goat(100860894) prostaglandin I2 (prostacyclin) synthase
- cow(282021) prostaglandin I2 (prostacyclin) synthase
- domestic guinea pig(100734621) prostaglandin I2 (prostacyclin) synthase
- Zebrafish(559148) prostaglandin I2 (prostacyclin) synthase
- sheep(101116418) prostaglandin I2 (prostacyclin) synthase
- Horse(100071412) prostaglandin I2 (prostacyclin) synthase
- naked mole-rat(101700601) prostaglandin I2 (prostacyclin) synthase
- domestic cat(101082050) prostaglandin I2 (prostacyclin) synthase
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PTGIS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-PTGIS antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, human, mouse, rat
Aplicación
western blot
Monoclonal Anti-PTGIS, (C-terminal) antibody produced in mouse, clone 3B11, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
Small Molecule - Ligand
Referencia del producto
Descripción
Especie