Saltar al contenido
Merck

PRKCZ

protein kinase C, zeta

Sinónimos:
PKC-ZETA, PKC2
Especie:
ID UniProtKB:
ID del gen:
  • Human(5590) Summary: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(18762) protein kinase C, zeta
  • Rat(25522) protein kinase C, zeta
  • dog(479577) protein kinase C, zeta
  • chicken(419399) protein kinase C, zeta
  • domestic cat(101087851) protein kinase C, zeta
  • Domestic Rabbit(100009538) protein kinase C, zeta
  • sheep(101122295) protein kinase C, zeta
  • naked mole-rat(101699303) protein kinase C, zeta
  • domestic guinea pig(100734946) protein kinase C, zeta
  • cow(286877) protein kinase C, zeta
  • Zebrafish(555737) protein kinase C, zeta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PRKCZ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-PKC ζ antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PKC ζ Antibody, clone 1F20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay

western blot
Anti-Phospho-PKC zeta-T560 antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
western blot
Anti-phospho-PKC ζ (pThr410) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
UCN-01, ≥97% (HPLC), powder,
Especie
human
GSK690693, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
Protein Kinase Cζ isozyme human, ≥75% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PRKCZ,
Especie
human