PDK1
pyruvate dehydrogenase kinase, isozyme 1
Sinónimos:
Especie:
Human PDK1 (5163), Mouse Pdk1 (228026), Rat Pdk1 (116551), fruit fly Pdk1 (38017), Zebrafish pdk1 (555840), Thale Cress PDK1 (830330), Horse PDK1 (100064091), domestic guinea pig Pdk1 (100715937), naked mole-rat Pdk1 (101705587), sheep PDK1 (101113205) ...Más
ID UniProtKB:
ID del gen:
- Human(5163) Summary: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
- Mouse(228026) pyruvate dehydrogenase kinase, isoenzyme 1
- Rat(116551) pyruvate dehydrogenase kinase, isozyme 1
- fruit fly(38017) Phosphoinositide-dependent kinase 1
- Zebrafish(555840) pyruvate dehydrogenase kinase, isozyme 1
- Thale Cress(830330) 3'-phosphoinositide-dependent protein kinase 1
- Horse(100064091) pyruvate dehydrogenase kinase, isozyme 1
- domestic guinea pig(100715937) pyruvate dehydrogenase kinase, isozyme 1
- naked mole-rat(101705587) pyruvate dehydrogenase kinase, isozyme 1
- sheep(101113205) pyruvate dehydrogenase kinase, isozyme 1
- Domestic Rabbit(100351323) pyruvate dehydrogenase kinase, isozyme 1
- cow(528655) pyruvate dehydrogenase kinase, isozyme 1
- domestic cat(101092705) pyruvate dehydrogenase kinase, isozyme 1
- dog(476828) pyruvate dehydrogenase kinase, isozyme 1
- chicken(425972) pyruvate dehydrogenase kinase, isozyme 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Activator
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-PDH kinase 1 Antibody, clone 1C7-H1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-PDK1/PDHK1 Antibody, clone 5T6S8, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
western blot
Monoclonal Anti-PDK1 antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
PDHK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human