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Merck

PCGF2

polycomb group ring finger 2

Sinónimos:
MEL-18, RNF110, ZNF144
Especie:
ID UniProtKB:
ID del gen:
  • Human(7703) Summary: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(22658) polycomb group ring finger 2
  • Rat(287662) polycomb group ring finger 2
  • sheep(101120343) polycomb group ring finger 2
  • domestic cat(101087022) polycomb group ring finger 2
  • chicken(425919) polycomb group ring finger 2
  • naked mole-rat(101721189) polycomb group ring finger 2
  • dog(491035) polycomb group ring finger 2
  • Horse(100055282) polycomb group ring finger 2
  • cow(505147) polycomb group ring finger 2
  • domestic guinea pig(100719492) polycomb group ring finger 2

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-PCGF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-PCGF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-PCGF2 antibody produced in mouse, clone 4D6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human PCGF2 (2),
Especie
human
MISSION® esiRNA, targeting mouse Pcgf2,
Especie
mouse
MISSION® esiRNA, targeting human PCGF2,
Especie
human