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Merck

P2RY12

purinergic receptor P2Y, G-protein coupled, 12

Sinónimos:
ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
Especie:
ID UniProtKB:
ID del gen:
  • Human(64805) Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(70839) purinergic receptor P2Y, G-protein coupled 12
  • Rat(64803) purinergic receptor P2Y, G-protein coupled, 12
  • dog(442958) purinergic receptor P2Y, G-protein coupled, 12
  • cow(408007) purinergic receptor P2Y, G-protein coupled, 12
  • sheep(101117897) purinergic receptor P2Y, G-protein coupled, 12
  • naked mole-rat(101701294) purinergic receptor P2Y, G-protein coupled, 12
  • domestic cat(101094044) purinergic receptor P2Y, G-protein coupled, 12
  • domestic guinea pig(100720551) purinergic receptor P2Y, G-protein coupled, 12

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Uridine 5′-(trihydrogen diphosphate) sodium salt from Saccharomyces cerevisiae, 95-100%,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Ticagrelor, ≥98% (HPLC),
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Clopidogrel bisulfate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
(S)-(+)-Clopidogrel hydrogensulfate, ≥98% (HPLC),
Especie
human
Prasugrel, ≥98% (HPLC),
Especie
human
Clopidogrel Bisulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Ticlopidine hydrochloride, analytical standard, for drug analysis,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-P2RY12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-P2RY12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-P2RY12 Antibody, clone 2C12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-P2RY12 Antibody, clone 10B5.3.27, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-P2Y12 Receptor, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human P2RY12,
Especie
human
MISSION® esiRNA, targeting mouse P2ry12,
Especie
mouse