NR3C2
nuclear receptor subfamily 3, group C, member 2
Sinónimos:
MCR, MLR, MR, NR3C2VIT
Especie:
Human NR3C2 (4306), Mouse Nr3c2 (110784), Rat Nr3c2 (25672), sheep NR3C2 (101107046), cow NR3C2 (280861), cow NR3C2 (537614), domestic cat NR3C2 (101081977), Horse NR3C2 (100062570), dog NR3C2 (475461), chicken NR3C2 (374131) ...Más
ID UniProtKB:
ID del gen:
- Human(4306) Summary: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- Mouse(110784) nuclear receptor subfamily 3, group C, member 2
- Rat(25672) nuclear receptor subfamily 3, group C, member 2
- sheep(101107046) nuclear receptor subfamily 3, group C, member 2
- cow(280861) nuclear receptor subfamily 3, group C, member 2
- cow(537614) nuclear receptor subfamily 3, group C, member 2
- domestic cat(101081977) nuclear receptor subfamily 3, group C, member 2
- Horse(100062570) nuclear receptor subfamily 3, group C, member 2
- dog(475461) nuclear receptor subfamily 3, group C, member 2
- chicken(374131) nuclear receptor subfamily 3, group C, member 2
- domestic guinea pig(100735309) nuclear receptor subfamily 3, group C, member 2
- Zebrafish(562171) nuclear receptor subfamily 3, group C, member 2
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Small Molecule - Agonist
Referencia del producto
Descripción
Especie
Deoxycorticosterone acetate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Small Molecule - Antagonist
Referencia del producto
Descripción
Especie
Spironolactone Related Compound A, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-receptor de mineralocorticoides, clon 6G1, clone 6G1, from mouse,
Reactividad de especies
mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticuerpo anti-receptor de mineralocorticoides, clon 2D6, clone 2D6, from mouse,
Reactividad de especies
rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-NR3C2 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human, rabbit
Aplicación
immunohistochemistry
western blot
western blot
Anti-NR3C2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-NR3C2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
horse, human
Aplicación
western blot