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Merck

NFKBIA

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Sinónimos:
IKBA, MAD-3, NFKBI
Especie:
ID UniProtKB:
ID del gen:
  • Human(4792) Summary: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
  • Mouse(18035) nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • Rat(25493) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • naked mole-rat(101709256) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic guinea pig(100723189) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • domestic cat(101090622) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • sheep(780520) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • chicken(396093) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • dog(480291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • cow(282291) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Phospho-IκBα-Ser32/36 Antibody, clone 1I11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-Phospho-IκBα-S32/36 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-p-IκBα-Ser32 Antibody, clone 11D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, porcine
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

inhibition assay

western blot
Anti-IKB α Antibody, clone 6O8, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-IkappaB-α (pSer32/36) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
I?Bα, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Nfkbia,
Especie
mouse
MISSION® esiRNA, targeting human NFKBIA,
Especie
human