NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Sinónimos:
CI-75Kd, CI-75k, PRO1304
Especie:
Human NDUFS1 (4719), Mouse Ndufs1 (227197), Rat Ndufs1 (301458), Zebrafish ndufs1 (493605), chicken NDUFS1 (424102), domestic guinea pig Ndufs1 (100726311), naked mole-rat Ndufs1 (101698993), cow NDUFS1 (288380), sheep NDUFS1 (101115434), Goat NDUFS1 (100861376) ...Más
ID UniProtKB:
ID del gen:
- Human(4719) Summary: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
- Mouse(227197) NADH dehydrogenase (ubiquinone) Fe-S protein 1
- Rat(301458) NADH dehydrogenase (ubiquinone) Fe-S protein 1
- Zebrafish(493605) NADH dehydrogenase (ubiquinone) Fe-S protein 1
- chicken(424102) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- domestic guinea pig(100726311) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- naked mole-rat(101698993) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- cow(288380) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- sheep(101115434) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- Goat(100861376) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- domestic cat(101100747) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- dog(478880) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
- Horse(100066330) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-complejo I-75 KD, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, chimpanzee, human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-NDUFS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Número de producto
Descripción
Especie
1,1-Dimetilbiguanida hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
1,1-Dimetilbiguanida hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human