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Merck

MARCH4

membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase

Sinónimos:
MARCH-IV, RNF174
Especie:
ID UniProtKB:
ID del gen:
  • Human(57574) Summary: MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]
  • Mouse(381270) membrane-associated ring finger (C3HC4) 4
  • Rat(367295) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • sheep(101107500) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • Zebrafish(562065) membrane-associated ring finger (C3HC4) 4
  • Horse(100050538) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • cow(527624) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • dog(488515) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • naked mole-rat(101718651) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • domestic guinea pig(100725253) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • domestic cat(101082766) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-MARCH4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MARCH4,
Especie
human