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Merck

MAPK7

mitogen-activated protein kinase 7

Sinónimos:
BMK1, ERK4, ERK5, PRKM7
Especie:
ID UniProtKB:
ID del gen:
  • Human(5598) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(23939) mitogen-activated protein kinase 7
  • Rat(114509) mitogen-activated protein kinase 7
  • Zebrafish(541323) mitogen-activated protein kinase 7
  • domestic cat(101097357) mitogen-activated protein kinase 7
  • cow(537703) mitogen-activated protein kinase 7
  • dog(489532) mitogen-activated protein kinase 7
  • Domestic Rabbit(100338535) mitogen-activated protein kinase 7
  • sheep(101110073) mitogen-activated protein kinase 7
  • naked mole-rat(101726391) mitogen-activated protein kinase 7
  • domestic guinea pig(100728396) mitogen-activated protein kinase 7

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ERK5 Antibody, clone 5C1P5, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
Anti-ERK5 Antibody, clone 2H15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, porcine
Aplicación
ELISA
affinity binding assay

immunofluorescence

immunohistochemistry

western blot
Anti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
Anti-MAPK7 (ab2) antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-MAPK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence

Proteins

Referencia del producto
Descripción
Especie
ERK5, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MAPK7,
Especie
human
MISSION® esiRNA, targeting mouse Mapk7,
Especie
mouse