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Merck

LOXL2

lysyl oxidase-like 2

Sinónimos:
LOR2, WS9-14
Especie:
ID UniProtKB:
ID del gen:
  • Human(4017) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
  • Mouse(94352) lysyl oxidase-like 2
  • Rat(290350) lysyl oxidase-like 2
  • domestic guinea pig(100729973) lysyl oxidase-like 2
  • chicken(419533) lysyl oxidase-like 2
  • domestic cat(101084102) lysyl oxidase-like 2
  • dog(486118) lysyl oxidase-like 2
  • cow(532684) lysyl oxidase-like 2
  • Domestic Rabbit(100346678) lysyl oxidase-like 2
  • sheep(101120812) lysyl oxidase-like 2
  • naked mole-rat(101700042) lysyl oxidase-like 2

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-LOXL2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-LOXL2 Antibody, clone GS341, ,
Reactividad de especies
human, mouse
Aplicación
ELISA
inhibition assay

western blot
Anti-LOXL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-LOXL2, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-LOXL2, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

Referencia del producto
Descripción
Especie
LOXL2 human, recombinant, expressed in FreeStyle 293-F cells, ≥86% (SDS-PAGE),
Especie
human
Lysyl Oxidase-like 2 (LOXL2) FLAG-tag (Sf9-derived) human, recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Loxl2,
Especie
mouse
MISSION® esiRNA, targeting human LOXL2,
Especie
human