IDO1
indoleamine 2,3-dioxygenase 1
Sinónimos:
IDO, IDO-1, INDO
Especie:
Human IDO1 (3620), Mouse Ido1 (15930), Rat Ido1 (66029), Zebrafish ido1 (571967), dog IDO1 (475574), domestic guinea pig Ido1 (100728309), naked mole-rat Ido1 (101723745), domestic cat IDO1 (101096977), cow IDO1 (506281), sheep IDO1 (100196903)
ID UniProtKB:
ID del gen:
- Human(3620) Summary: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
- Mouse(15930) indoleamine 2,3-dioxygenase 1
- Rat(66029) indoleamine 2,3-dioxygenase 1
- Zebrafish(571967) indoleamine 2,3-dioxygenase 1
- dog(475574) indoleamine 2,3-dioxygenase 1
- domestic guinea pig(100728309) indoleamine 2,3-dioxygenase 1
- naked mole-rat(101723745) indoleamine 2,3-dioxygenase 1
- domestic cat(101096977) indoleamine 2,3-dioxygenase 1
- cow(506281) indoleamine 2,3-dioxygenase 1
- sheep(100196903) indoleamine 2,3-dioxygenase 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-IDO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-IDO1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-IDO-1 Antibody, clone 4B7 | MABF850, clone 4B7, from mouse,
Reactividad de especies
mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Indoleamine 2,3-dioxygenase Antibody, clone 10.1, clone 10.1, Chemicon®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Ido1, clone 8G11 Antibody, clone 8G11, from mouse,
Reactividad de especies
mouse
Aplicación
flow cytometry
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie