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Merck

IAPP

islet amyloid polypeptide

Sinónimos:
DAP, IAP
Especie:
ID UniProtKB:
ID del gen:
  • Human(3375) Summary: Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq, Apr 2011]
  • Mouse(15874) islet amyloid polypeptide
  • Rat(24476) islet amyloid polypeptide
  • dog(403909) islet amyloid polypeptide
  • domestic guinea pig(100135550) islet amyloid polypeptide
  • naked mole-rat(101702167) islet amyloid polypeptide
  • cow(100138011) islet amyloid polypeptide
  • sheep(101120402) islet amyloid polypeptide
  • Domestic Rabbit(100009489) islet amyloid polypeptide
  • chicken(396362) islet amyloid polypeptide
  • domestic cat(751513) islet amyloid polypeptide

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-IAPP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-IAPP antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
Anti-Amylin antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot
Anti-IAPP (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot
Anti-IAPP (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, horse, human, rabbit
Aplicación
western blot

Proteins

Referencia del producto
Descripción
Especie
Diabetes Associated Peptide Amide human, ≥97% (HPLC),
Especie
human
Acetyl-Diabetes Associated Peptide Fragment 8-37 amide trifluoroacetate salt, sequence human, ≥95% (HPLC),
Especie
human