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Merck

HEXB

hexosaminidase B (beta polypeptide)

Sinónimos:
ENC-1AS
Especie:
ID UniProtKB:
ID del gen:
  • Human(3074) Summary: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008]
  • Mouse(15212) hexosaminidase B
  • Rat(294673) hexosaminidase B
  • naked mole-rat(101713145) hexosaminidase B (beta polypeptide)
  • chicken(427204) hexosaminidase B (beta polypeptide)
  • dog(478100) hexosaminidase B (beta polypeptide)
  • domestic cat(493928) hexosaminidase B (beta polypeptide)
  • sheep(101111906) hexosaminidase B (beta polypeptide)
  • cow(618571) hexosaminidase B (beta polypeptide)
  • Domestic Rabbit(100009508) hexosaminidase B (beta polypeptide)
  • domestic guinea pig(100731613) hexosaminidase B (beta polypeptide)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HEXB antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot
Anti-HEXB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-HEXB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Hexb,
Especie
mouse
MISSION® esiRNA, targeting human HEXB,
Especie
human