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Merck

GSTM1

glutathione S-transferase mu 1

Sinónimos:
GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1
Especie:
Human GSTM1 (2944), Mouse Gstm1 (14862), Rat Gstm1 (24423), cow GSTM1 (783879), cow GSTM1 (327709), domestic guinea pig Gstm1 (100731426)
ID UniProtKB:
P09488, Q5GHG0, Q6FH88, Q8TC98, Q9UC96
ID del gen:
  • Human(2944) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14862) glutathione S-transferase, mu 1
  • Rat(24423) glutathione S-transferase mu 1
  • cow(783879) glutathione S-transferase mu 1
  • cow(327709) glutathione S-transferase M1
  • domestic guinea pig(100731426) glutathione S-transferase mu 1

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ELISA

Referencia del producto
Descripción
Especie
RAB1496
Human GSTM1 ELISA, for serum, plasma and cell culture supernatants,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA048652
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
SAB5700272
Anti-GSTM1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot
HPA055972
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
HPA055973
Anti-GSTM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
WH0002944M1
Monoclonal Anti-GSTM1 antibody produced in mouse, clone 3B10, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA

Cell Lines

Referencia del producto
Descripción
Especie
GS65
GST M1-1, Recombinant Human, ,
Especie
human

Kits

Referencia del producto
Descripción
Especie
CS0410
Glutathione-S-Transferase (GST) Assay Kit, sufficient for 500 multiwell tests,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU115801
MISSION® esiRNA, targeting human GSTM1,
Especie
human