Saltar al contenido
Merck

GEMIN2

gem (nuclear organelle) associated protein 2

Sinónimos:
SIP1, SIP1-delta
Especie:
ID UniProtKB:
ID del gen:
  • Human(8487) Summary: This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]
  • Mouse(66603) gem (nuclear organelle) associated protein 2
  • Rat(84404) gem (nuclear organelle) associated protein 2
  • domestic cat(101083009) gem (nuclear organelle) associated protein 2
  • domestic guinea pig(100732674) gem (nuclear organelle) associated protein 2
  • naked mole-rat(101715665) gem (nuclear organelle) associated protein 2
  • sheep(101122894) gem (nuclear organelle) associated protein 2
  • dog(610087) gem (nuclear organelle) associated protein 2
  • Zebrafish(550271) gem (nuclear organelle) associated protein 2
  • chicken(423336) gem (nuclear organelle) associated protein 2
  • cow(510259) gem (nuclear organelle) associated protein 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Gemin2 Antibody, clone 2E17, clone 2E17, from mouse,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-GEMIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-GEMIN2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-GEMIN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GEMIN2,
Especie
human