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Merck

FMO5

flavin containing monooxygenase 5

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2330) Summary: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  • Mouse(14263) flavin containing monooxygenase 5
  • Rat(246248) flavin containing monooxygenase 5
  • domestic guinea pig(100135521) flavin containing monooxygenase 5
  • cow(788719) flavin containing monooxygenase 5
  • Domestic Rabbit(100009064) flavin containing monooxygenase 5
  • Zebrafish(794311) flavin containing monooxygenase 5
  • chicken(100857694) flavin containing monooxygenase 5
  • domestic cat(101092533) flavin containing monooxygenase 5
  • sheep(101113713) flavin containing monooxygenase 5
  • Horse(100065455) flavin containing monooxygenase 5
  • dog(475819) flavin containing monooxygenase 5

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-FMO5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-FMO5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-FMO5 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot

Proteins

Referencia del producto
Descripción
Especie
Flavin-Containing Monooxygenase-5, Microsomes human, recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human FMO5,
Especie
human
MISSION® esiRNA, targeting mouse Fmo5,
Especie
mouse