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Merck

FGFR1OP

FGFR1 oncogene partner

Sinónimos:
FOP
Especie:
ID UniProtKB:
ID del gen:
  • Human(11116) Summary: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
  • Mouse(75296) Fgfr1 oncogene partner
  • Rat(365103) FGFR1 oncogene partner
  • sheep(101115039) FGFR1 oncogene partner
  • domestic cat(101099885) FGFR1 oncogene partner
  • dog(612453) FGFR1 oncogene partner
  • Zebrafish(415215) FGFR1 oncogene partner
  • chicken(421568) FGFR1 oncogene partner
  • domestic guinea pig(100728960) FGFR1 oncogene partner
  • cow(506246) FGFR1 oncogene partner
  • naked mole-rat(101707272) FGFR1 oncogene partner

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-FGFR1OP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-FGFR1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Monoclonal Anti-FGFR1OP antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-FGFR1OP antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human FGFR1OP,
Especie
human
MISSION® esiRNA, targeting mouse Fgfr1op,
Especie
mouse