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Merck

F9

coagulation factor IX

Sinónimos:
FIX, HEMB, P19, PTC, THPH8
Especie:
ID UniProtKB:
ID del gen:
  • Human(2158) Summary: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq, Jul 2008]
  • Mouse(14071) coagulation factor IX
  • Rat(24946) coagulation factor IX
  • naked mole-rat(101724977) coagulation factor IX
  • domestic guinea pig(100135464) coagulation factor IX
  • chicken(374258) coagulation factor IX
  • dog(404015) coagulation factor IX
  • Domestic Rabbit(100009113) coagulation factor IX
  • sheep(443316) coagulation factor IX
  • cow(280688) coagulation factor IX
  • Horse(100054449) coagulation factor IX
  • domestic cat(493973) coagulation factor IX

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Factor IX antibody, Mouse monoclonal, clone HIX-1, purified from hybridma cell culture,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-Factor IX antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
dot blot

western blot
Anti-Factor IX antibody, Mouse monoclonal, clone HIX-5, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
ELISA
western blot

Proteins

Referencia del producto
Descripción
Especie
Factor IX human, aqueous glycerol solution, ≥145 units/mg protein,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human F9,
Especie
human