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Merck

DHCR24

24-dehydrocholesterol reductase

Sinónimos:
DCE, Nbla03646, SELADIN1, seladin-1
Especie:
ID UniProtKB:
ID del gen:
  • Human(1718) Summary: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • Mouse(74754) 24-dehydrocholesterol reductase
  • Rat(298298) 24-dehydrocholesterol reductase
  • domestic guinea pig(100714000) 24-dehydrocholesterol reductase
  • naked mole-rat(101703975) 24-dehydrocholesterol reductase
  • dog(489573) 24-dehydrocholesterol reductase
  • domestic cat(101098730) 24-dehydrocholesterol reductase
  • Horse(100034055) 24-dehydrocholesterol reductase
  • cow(533726) 24-dehydrocholesterol reductase
  • sheep(101123162) 24-dehydrocholesterol reductase
  • Zebrafish(494102) 24-dehydrocholesterol reductase
  • chicken(424661) 24-dehydrocholesterol reductase

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, human, mouse, rabbit, rat
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Triparanol, ≥97% (HPLC), powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Dhcr24,
Especie
mouse
MISSION® esiRNA, targeting human DHCR24,
Especie
human