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Merck

CYBB

cytochrome b-245, beta polypeptide

Sinónimos:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Especie:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), cow CYBB (281112), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801), dog CYBB (491825), chicken CYBB (418581), Zebrafish cybb (393386)
ID UniProtKB:
P04839, A8K138, Q2PP16
ID del gen:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA051227
Anti-CYBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
07-024
Anti-gp91-phox Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
MABS2195
Anti-gp91phox (NOX2) Antibody, ,
Reactividad de especies
human
Aplicación
flow cytometry
western blot
AV44276
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rabbit, rat
Aplicación
western blot
SAB5702937
Anti-NOX2/gp91phox Antibody, clone 2Y8W3, Rabbit Monoclonal, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU010941
MISSION® esiRNA, targeting human CYBB,
Especie
human