COPS5
COP9 signalosome subunit 5
Sinónimos:
CSN5, JAB1, MOV-34, SGN5
Especie:
Human COPS5 (10987), Mouse Cops5 (26754), Rat Cops5 (312916), domestic cat COPS5 (101092084), Zebrafish cops5 (393698), chicken COPS5 (426579), domestic guinea pig Cops5 (100716886), naked mole-rat Cops5 (101710038), Horse COPS5 (100051846), cow COPS5 (507179) ...Más
ID UniProtKB:
ID del gen:
- Human(10987) Summary: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
- Mouse(26754) COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)
- Rat(312916) COP9 signalosome subunit 5
- domestic cat(101092084) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
- Zebrafish(393698) COP9 constitutive photomorphogenic homolog subunit 5
- chicken(426579) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
- domestic guinea pig(100716886) COP9 signalosome subunit 5
- naked mole-rat(101710038) COP9 signalosome subunit 5
- Horse(100051846) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
- cow(507179) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
- sheep(101101995) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
- dog(477901) COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-COPS5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-COPS5 antibody produced in mouse, ,
Reactividad de especies
drosophila, human, mouse, rat
Aplicación
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-COPS5 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
western blot
western blot
Anti-COPS5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-JAB1/CSN5/COPS5 antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
esiRNA
Referencia del producto
Descripción
Especie