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Merck

CLPS

colipase, pancreatic

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(1208) Summary: The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(109791) colipase, pancreatic
  • Rat(25680) colipase, pancreatic
  • cow(525923) colipase, pancreatic
  • Horse(100053646) colipase, pancreatic
  • domestic cat(101100391) colipase, pancreatic
  • Domestic Rabbit(100009061) colipase, pancreatic
  • sheep(101119081) colipase, pancreatic
  • dog(403970) colipase, pancreatic
  • naked mole-rat(101718096) colipase, pancreatic
  • chicken(771102) colipase, pancreatic
  • domestic guinea pig(100723751) colipase, pancreatic

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CLPS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-Colipase Antibody, serum, from rabbit,
Reactividad de especies
mouse
Aplicación
western blot
Monoclonal Anti-CLPS antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
Monoclonal Anti-CLPS, (C-terminal) antibody produced in mouse, clone 4G3, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot

Proteins

Número de producto
Descripción
Especie
Colipase from porcine pancreas, essentially salt-free, lyophilized powder,
Especie

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Clps,
Especie
mouse
MISSION® esiRNA, targeting human CLPS,
Especie
human