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Merck

CHRM5

cholinergic receptor, muscarinic 5

Sinónimos:
HM5
Especie:
Human CHRM5 (1133), Mouse Chrm5 (213788), Rat Chrm5 (53949), naked mole-rat Chrm5 (101719201), Domestic Rabbit CHRM5 (100342984), dog CHRM5 (487472), Horse CHRM5 (100057856), cow CHRM5 (281686), sheep CHRM5 (101110766), domestic cat CHRM5 (101097246) ...Más
ID UniProtKB:
P08912, Q96RG7
ID del gen:
  • Human(1133) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]
  • Mouse(213788) cholinergic receptor, muscarinic 5
  • Rat(53949) cholinergic receptor, muscarinic 5
  • naked mole-rat(101719201) cholinergic receptor, muscarinic 5
  • Domestic Rabbit(100342984) cholinergic receptor, muscarinic 5
  • dog(487472) cholinergic receptor, muscarinic 5
  • Horse(100057856) cholinergic receptor, muscarinic 5
  • cow(281686) cholinergic receptor, muscarinic 5
  • sheep(101110766) cholinergic receptor, muscarinic 5
  • domestic cat(101097246) cholinergic receptor, muscarinic 5
  • chicken(428881) cholinergic receptor, muscarinic 5
  • domestic guinea pig(100379240) cholinergic receptor, muscarinic 5

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Small Molecule - Agonist

Número de producto
Descripción
Especie
P6503
Pilocarpine hydrochloride, ≥99% (titration), powder,
Especie
human
A2251
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Especie
human
P6628
Pilocarpine nitrate salt, ≥98% (HPLC),
Especie
human
O100
Oxotremorine M, solid,
Especie
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Especie
human

Small Molecule - Antagonist

Número de producto
Descripción
Especie
S1875
(−)-Scopolamine hydrobromide trihydrate, >95% (HPLC), powder,
Especie
human
A0257
Atropine sulfate salt monohydrate, ≥97% (TLC), crystalline,
Especie
human
S8502
(−)-Scopolamine methyl bromide, ≥98% (HPLC), powder,
Especie
human
P8891
Propantheline bromide, ≥97% (TLC), powder,
Especie
human
S7882
(−)-Scopolamine N-butyl bromide, ≥98% (TLC), powder,
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
HPA013172
Anti-CHRM5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Especie
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Especie
human
51330
Harmaline, ≥95%,
Especie
human, rat

Small Molecule - Ligand

Número de producto
Descripción
Especie
A138
Aminobenztropine, solid,
Especie
human

Proteins

Número de producto
Descripción
Especie
HTS075M
ChemiScreen Membrane Preparation
Recombinant Human M5 Muscarinic Acetylcholine Receptor, Human M5 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Especie
human