CDK11B
cyclin-dependent kinase 11B
Sinónimos:
CDC2L1, CDK11, CDK11-p110, CDK11-p46, CDK11-p58, CLK-1, PK58, p58, p58CDC2L1, p58CLK-1
Especie:
ID UniProtKB:
ID del gen:
- Human(984) Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq, Jul 2008]
- Mouse(12537) cyclin-dependent kinase 11B
- Rat(252879) cyclin-dependent kinase 11B
- Zebrafish(494103) cyclin-dependent kinase 11B
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Antibodies
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Descripción
Reactividad de especies
Aplicación
Anti-CDK11A/CDK11B antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
esiRNA
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Descripción
Especie