Saltar al contenido
Merck

CCND3

cyclin D3

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(896) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  • Mouse(12445) cyclin D3
  • Rat(25193) cyclin D3
  • domestic cat(101101311) cyclin D3
  • Domestic Rabbit(100009038) cyclin D3
  • domestic guinea pig(100718785) cyclin D3
  • naked mole-rat(101708062) cyclin D3
  • sheep(100147798) cyclin D3
  • dog(608847) cyclin D3
  • chicken(419928) cyclin D3
  • cow(540547) cyclin D3
  • Zebrafish(449996) cyclin D3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Cyclin D3 Antibody, clone 4C5C8, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
Anti-CCND3 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-Cyclin D3 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Anti-Cyclin D3 antibody, Rabbit monoclonal, clone SP207, recombinant, expressed in proprietary host, affinity isolated antibody,
Reactividad de especies
bovine, human, mouse, rat
Aplicación
flow cytometry
immunohistochemistry

western blot
Anti-CCND3 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
CDK4/CyclinD3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CCND3,
Especie
human