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Merck

ATP6V1G2

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2

Sinónimos:
ATP6G, ATP6G2, NG38, VMA10
Especie:
ID UniProtKB:
ID del gen:
  • Human(534) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene. [provided by RefSeq, Feb 2011]
  • Mouse(66237) ATPase, H+ transporting, lysosomal V1 subunit G2
  • Rat(368044) ATPase, H+ transporting, lysosomal V1 subunit G2
  • naked mole-rat(101720978) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
  • domestic guinea pig(100723558) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
  • sheep(101123332) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
  • domestic cat(101084539) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
  • cow(514368) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
  • dog(474840) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ATP6V1G2 (6-20) antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human
Aplicación
western blot
Anti-ATP6V1G2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Atp6v1g2,
Especie
mouse
MISSION® esiRNA, targeting human ATP6V1G2,
Especie
human