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Merck

ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

Sinónimos:
ATP6C, ATP6L, ATPL, VATL, VPPC, Vma3
Especie:
ID UniProtKB:
ID del gen:
  • Human(527) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010]
  • Mouse(11984) ATPase, H+ transporting, lysosomal V0 subunit C
  • Rat(170667) ATPase, H+ transporting, lysosomal V0 subunit C
  • dog(479877) ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
  • cow(550622) ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
  • domestic guinea pig(100735418) ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
  • sheep(443003) ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
  • naked mole-rat(101709243) ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
  • domestic cat(101101434) ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
  • chicken(416753) ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ATP6V0C antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot
ANTI-ATP6V0C(C-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ATP6V0C, RP11-20I23.1,
Especie
human
MISSION® esiRNA, targeting mouse Atp6v0c,
Especie
mouse